Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2E1 | P05181 | 1/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | PSEN1 | P49768 | 4/20 | 0.38 |
| ▸ | PSEN2 | P49810 | 4/20 | 0.38 |
| ▸ | APH1B | Q8WW43 | 4/20 | 0.38 |
| ▸ | NCSTN | Q92542 | 4/20 | 0.38 |
| ▸ | APH1A | Q96BI3 | 4/20 | 0.38 |
| ▸ | PSENEN | Q9NZ42 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | GBA1 | P04062 | 1/20 | 0.37 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.36 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6127814 | 0.81 | CYP2E1 (0.46) | CYP2E1CYP2A6PSEN1PSEN2APH1B | |
| SCHEMBL27381147 | 0.81 | GRIN2D (0.38) | ALDH1A1GBA1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL11962606 | 0.79 | CYP2E1 (0.44) | CYP2E1CYP2A6PSEN1PSEN2APH1B | |
| SCHEMBL22199018 | 0.79 | CYP2E1 (0.44) | CYP2E1CYP2A6PSEN1PSEN2APH1B | |
| SCHEMBL28674063 | 0.79 | PSEN1 (0.48) | CYP2E1CYP2A6PSEN1PSEN2APH1B | |
| SCHEMBL2899675 | 0.79 | GBA1 (0.37) | ALDH1A1GBA1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL24780239 | 0.76 | CYP1A2 (0.42) | CYP2E1CYP2A6PSEN1PSEN2APH1B | |
| SCHEMBL6124272 | 0.76 | CYP2E1 (0.41) | CYP2E1CYP2A6ALDH1A1PSEN1PSEN2 | |
| SCHEMBL4666728 | 0.76 | CYP3A4 (0.56) | CYP2E1CYP2A6GAAPSEN1PSEN2 | |
| SCHEMBL7881481 | 0.76 | KDM4E (0.47) | CYP2E1CYP2A6GAAALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4676547-A2 | ALPHA-SYNUCLEIN BINDERS AND METHODS OF USE | Merck Sharp & Dohme LLC (US) | 2026-01-14 | — | — | EP | disclosed |
| WO-2024186584-A2 | ALPHA-SYNUCLEIN BINDERS AND METHODS OF USE | MERCK SHARP & DOHME LLC (US) | 2024-09-12 | — | — | WO | disclosed |