Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.62 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.62 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.62 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.62 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.62 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.62 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.62 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.62 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.62 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.62 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.62 |
| ▸ | NPC1 | O15118 | 3/20 | 0.61 |
| ▸ | RAB9A | P51151 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | GRM4 | Q14833 | 8/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28611795 | 1.00 | HDAC6 (0.62) | HDAC6HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL3381752 | 0.88 | NPC1 (0.59) | HDAC6HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL18906043 | 0.85 | HDAC1 (0.64) | HDAC6HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL28613060 | 0.85 | MCL1 (0.68) | HDAC6HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL29643990 | 0.85 | MCL1 (0.68) | HDAC6HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL11446166 | 0.84 | POLB (0.60) | HDAC6HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL7989152 | 0.84 | HDAC1 (0.77) | HDAC6HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL3564099 | 0.84 | HDAC1 (0.62) | HDAC6HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL28921792 | 0.84 | NPC1 (0.54) | HDAC6HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL28625315 | 0.84 | GRM4 (0.59) | HDAC6NPC1RAB9AGRM4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118459438-A | Synthesis method of iodine-catalyzed N-acyl-2-hydroxy-indol-3-one compound | 延安大学 | 2024-08-09 | — | — | CN | disclosed |