Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 2/20 | 0.77 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.77 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.77 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.77 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.77 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.77 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.77 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.77 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.77 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.77 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.77 |
| ▸ | NPC1 | O15118 | 3/20 | 0.70 |
| ▸ | RAB9A | P51151 | 3/20 | 0.70 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.59 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.59 |
| ▸ | RELA | Q04206 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | CES2 | O00748 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4522324 | 0.90 | HDAC1 (0.69) | HDAC1HDAC6HDAC3HDAC4HDAC7 | |
| SCHEMBL5711050 | 0.89 | HDAC1 (0.68) | HDAC1HDAC6HDAC3HDAC4HDAC7 | |
| SCHEMBL29531380 | 0.87 | NPC1 (0.79) | HDAC1HDAC6HDAC3HDAC4HDAC7 | |
| SCHEMBL2384990 | 0.87 | HDAC1 (1.00) | HDAC1HDAC6HDAC3HDAC4HDAC7 | |
| SCHEMBL30763136 | 0.87 | HDAC3 (0.71) | HDAC1HDAC6HDAC3HDAC4HDAC7 | |
| Ammonia Solution, Strong SCHEMBL20302203 | 0.87 | MCL1 (0.69) | HDAC1HDAC6HDAC3HDAC4HDAC7 | |
| SCHEMBL30416073 | 0.87 | HDAC1 (1.00) | HDAC1HDAC6HDAC3HDAC4HDAC7 | |
| SCHEMBL5285570 | 0.87 | HDAC3 (0.71) | HDAC1HDAC6HDAC3HDAC4HDAC7 | |
| SCHEMBL12437777 | 0.87 | NPC1 (0.79) | HDAC1HDAC6HDAC3HDAC4HDAC7 | |
| SCHEMBL18906043 | 0.86 | HDAC1 (0.64) | HDAC1HDAC6HDAC3HDAC4HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6191146-B1 | BACTERICIDES, FUNGICIDES, VIRICIDES | SMITHKLINE BEECHAM CORPORATION | 2001-02-20 | — | — | US | claimed |
| US-10910642-B1 | Redox flow battery having ligand-metal complex | TRIAD NATIONAL SECURITY, LLC (US) | 2021-02-02 | — | — | US | disclosed |
| US-8247399-B2 | Photoactive metal nitrosyls for blood pressure regulation and cancer therapy | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2012-08-21 | — | — | US | disclosed |
| US-20110152230-A1 | Photoactive Metal Nitrosyls For Blood Pressure Regulation And Cancer Therapy | THE REGENT OF THE UNIVERSITY OF CALIFORNIA | 2011-06-23 | — | — | US | disclosed |
| US-7582623-B2 | Ruthenium, manganese and ferric complexes with a polydentate ligand of carboxamide/pyridyl and nitrosyl ; targeted delivery of nitric oxide by applying of low power light; catherization; cysteine protease inhibiters; antitumor/carcinogenic agents; immunotherapy; muscle relaxants; side effect reduction | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2009-09-01 | — | — | US | disclosed |
| US-6191146-B1 | BACTERICIDES, FUNGICIDES, VIRICIDES | SMITHKLINE BEECHAM CORPORATION | 2001-02-20 | — | — | US | disclosed |
| EP-0866700-A4 | HEMOREGULATORY COMPOUNDS | SMITHKLINE BEECHAM CORP (US) | 1999-04-07 | — | — | EP | disclosed |
| EP-0866700-A1 | HEMOREGULATORY COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 1998-09-30 | — | — | EP | disclosed |
| WO-1997017958-A1 | HEMOREGULATORY COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 1997-05-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110152230-A1 | Photoactive Metal Nitrosyls For Blood Pressure Regulation And Cancer Therapy | NOS2, NOS3, NOS1 | HDAC1 1525/4885HDAC6 2322/4885HDAC3 2435/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.