SCHEMBL31087686

SCHEMBL31087686

Cc1nc2cc(N)ccc2nc1-c1ccc(N)cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 7/20 0.61
TLR9 Q9NR96 2/20 0.61
ATM Q13315 1/20 0.61
PIK3CG P48736 1/20 0.49
MAPT P10636 9/20 0.46
ALDH1A1 P00352 8/20 0.46
MEN1 O00255 6/20 0.46
LMNA P02545 3/20 0.46
GPR55 Q9Y2T6 1/20 0.46
KDM4E B2RXH2 9/20 0.43
L3MBTL1 Q9Y468 3/20 0.43
CDC7 O00311 1/20 0.43
EEF2K O00418 1/20 0.43
PLK4 O00444 1/20 0.43
AURKA O14965 1/20 0.43
DYRK3 O43781 1/20 0.43
RPS6KA5 O75582 1/20 0.43
PRKD3 O94806 1/20 0.43
MAP4K4 O95819 1/20 0.43
PIM1 P11309 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22288240 1.00 KMT2A (0.61) KMT2ATLR9ATMPIK3CGMAPT
SCHEMBL22288213 1.00 KMT2A (0.61) KMT2ATLR9ATMPIK3CGMAPT
SCHEMBL12964185 0.93 KMT2A (0.57) KMT2ATLR9ATMPIK3CGMAPT
SCHEMBL12964181 0.90 KMT2A (0.54) KMT2ATLR9ATMPIK3CGMAPT
SCHEMBL12964189 0.90 KMT2A (0.73) KMT2ATLR9ATMPIK3CGMAPT
SCHEMBL12964188 0.90 KMT2A (0.54) KMT2ATLR9ATMPIK3CGMAPT
SCHEMBL12964204 0.90 KMT2A (0.77) KMT2ATLR9ATMPIK3CGMAPT
SCHEMBL1550580 0.90 KMT2A (0.77) KMT2ATLR9ATMPIK3CGMAPT
SCHEMBL12964182 0.88 KMT2A (0.51) KMT2ATLR9ATMMAPTALDH1A1
SCHEMBL18082970 0.87 KMT2A (0.50) KMT2ATLR9ATMPIK3CGMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118546355-A High-heat-resistance and high-strength transparent nylon material and preparation method thereof 濮阳市盛通聚源新材料有限公司 2024-08-27 CN disclosed