Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | THRB | P10828 | 2/20 | 0.46 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.45 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.45 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.45 |
| ▸ | DTYMK | P23919 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | VEGFA | P15692 | 1/20 | 0.42 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31088395 | 1.00 | PTGDR2 (0.47) | PTGDR2TP53THRBENPP2DDB1 | |
| SCHEMBL30130208 | 0.93 | ENPP2 (0.50) | PTGDR2TP53THRBENPP2DDB1 | |
| SCHEMBL31088390 | 0.90 | PTGDR2 (0.51) | PTGDR2THRBENPP2DDB1CRBN | |
| SCHEMBL30130278 | 0.85 | DDB1 (0.50) | ENPP2DDB1CRBNDTYMKHDAC1 | |
| SCHEMBL30130263 | 0.85 | DDB1 (0.50) | PTGDR2ENPP2DDB1CRBNDTYMK | |
| SCHEMBL24914777 | 0.85 | ENPP2 (0.54) | PTGDR2ENPP2DDB1CRBNDTYMK | |
| SCHEMBL30130265 | 0.84 | ENPP2 (0.51) | TP53ENPP2DDB1CRBNHDAC1 | |
| SCHEMBL30130231 | 0.84 | DDB1 (0.49) | ENPP2DDB1CRBNDTYMKHDAC1 | |
| SCHEMBL30130284 | 0.84 | DDB1 (0.51) | PTGDR2ENPP2DDB1CRBNDTYMK | |
| SCHEMBL31119379 | 0.84 | ENPP2 (0.49) | PTGDR2TP53ENPP2DDB1CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024199457-A1 | COMPOUND HAVING RING FUSED STRUCTURE, PREPARATION METHOD THEREFOR AND USE THEREOF, AND PHARMACEUTICAL COMPOSITION AND USE THEREOF | 苏州安赛隆医药科技有限公司 | 2024-10-03 | — | — | WO | disclosed |