Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 7/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.40 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23145355 | 0.78 | USP2 (0.45) | USP2SMN1; SMN2GPR119RECQLNAMPT | |
| SCHEMBL1344048 | 0.77 | USP2 (0.50) | USP2SMN1; SMN2GPR119RECQLNAMPT | |
| SCHEMBL24188210 | 0.77 | USP2 (0.51) | USP2SMN1; SMN2GPR119RECQLNAMPT | |
| SCHEMBL20618024 | 0.75 | HPGD (0.46) | USP2SMN1; SMN2GPR119RECQLKDM4E | |
| SCHEMBL5857800 | 0.75 | USP2 (0.49) | USP2SMN1; SMN2GPR119RECQLKDM4E | |
| SCHEMBL38665956 | 0.75 | USP2 (0.45) | USP2SMN1; SMN2GPR119RECQLNAMPT | |
| SCHEMBL30295739 | 0.75 | USP2 (0.45) | USP2SMN1; SMN2GPR119RECQLNAMPT | |
| SCHEMBL21952178 | 0.75 | USP2 (0.45) | USP2SMN1; SMN2GPR119RECQLNAMPT | |
| SCHEMBL18330199 | 0.75 | USP2 (0.45) | USP2SMN1; SMN2GPR119RECQLNAMPT | |
| SCHEMBL26822575 | 0.75 | USP2 (0.45) | USP2SMN1; SMN2GPR119RECQLNAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024175907-A1 | MACROCYCLIC ALPHA4BETA7 INTEGRIN INHIBITORS | C4X DISCOVERY LIMITED (GB) | 2024-08-29 | — | — | WO | disclosed |