Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.33 |
| ▸ | OXTR | P30559 | 1/20 | 0.33 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.31 |
| ▸ | TUBB | P07437 | 1/20 | 0.31 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.31 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.31 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.31 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.31 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.31 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.31 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.31 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.31 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29611967 | 0.85 | MAPT (0.41) | MAPTGAAMCOLN3NPSR1POLB | |
| SCHEMBL21459929 | 0.85 | MAPT (0.41) | MAPTGAAMCOLN3NPSR1POLB | |
| SCHEMBL21459932 | 0.85 | MAPT (0.41) | MAPTGAAMCOLN3NPSR1POLB | |
| SCHEMBL16454234 | 0.84 | KDM4E (0.36) | NPSR1MEN1KMT2A | |
| SCHEMBL21598907 | 0.82 | NPSR1 (0.32) | NPSR1MEN1KMT2A | |
| SCHEMBL17808200 | 0.81 | HPGD (0.33) | GAA | |
| SCHEMBL20122631 | 0.80 | CYP3A4 (0.31) | — | |
| SCHEMBL31088740 | 0.78 | TUBB4A (0.33) | MAPTGAAMCOLN3MEN1KMT2A | |
| SCHEMBL31089176 | 0.78 | TUBB4A (0.31) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL3779382 | 0.76 | MAPT (0.45) | MAPTGAAMCOLN3NPSR1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024175907-A1 | MACROCYCLIC ALPHA4BETA7 INTEGRIN INHIBITORS | C4X DISCOVERY LIMITED (GB) | 2024-08-29 | — | — | WO | disclosed |