Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OTC | P00480 | 1/20 | 0.35 |
| ▸ | NPY4R | P50391 | 7/20 | 0.32 |
| ▸ | NPY1R | P25929 | 5/20 | 0.32 |
| ▸ | MME | P08473 | 5/20 | 0.32 |
| ▸ | ECE1 | P42892 | 5/20 | 0.32 |
| ▸ | NPY2R | P49146 | 3/20 | 0.32 |
| ▸ | NPY5R | Q15761 | 3/20 | 0.32 |
| ▸ | FNTA | P49354 | 1/20 | 0.32 |
| ▸ | FNTB | P49356 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | FPR2 | P25090 | 1/20 | 0.30 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.30 |
| ▸ | TMPRSS15 | P98073 | 1/20 | 0.30 |
| ▸ | MC4R | P32245 | 1/20 | 0.30 |
| ▸ | MC3R | P41968 | 1/20 | 0.30 |
| ▸ | MC1R | Q01726 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2991514 | 0.90 | OTC (0.42) | OTCNPY4RNPY1RMMEECE1 | |
| SCHEMBL2991505 | 0.90 | OTC (0.42) | OTCNPY4RNPY1RMMEECE1 | |
| SCHEMBL3098146 | 0.89 | OTC (0.34) | OTCNPY4RNPY1RMMEECE1 | |
| SCHEMBL3091575 | 0.88 | OTC (0.37) | OTCNPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL2992625 | 0.88 | OTC (0.37) | OTCNPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL27743692 | 0.86 | OTC (0.38) | OTCMMEECE1FNTAFNTB | |
| SCHEMBL2985776 | 0.86 | OTC (0.38) | OTCMMEECE1FNTAFNTB | |
| SCHEMBL3097987 | 0.84 | ALOX15 (0.36) | OTCNPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL2992620 | 0.82 | OTC (0.47) | OTCNPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL2992568 | 0.81 | CYP2D6 (0.35) | OTCNPY4RNPY1RNPY2RNPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100247463-A1 | N-(PHOSPHONOALKYL)-AMINO ACIDS, DERIVATIVES THEREOF AND COMPOSITIONS AND METHODS OF USE | YU RUEY J | 2010-09-30 | — | — | US | claimed |