Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIKFYVE | Q9Y2I7 | 4/20 | 0.61 |
| ▸ | MAPT | P10636 | 9/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.43 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | FES | P07332 | 1/20 | 0.40 |
| ▸ | FER | P16591 | 1/20 | 0.40 |
| ▸ | TYK2 | P29597 | 1/20 | 0.40 |
| ▸ | FRK | P42685 | 1/20 | 0.40 |
| ▸ | SYK | P43405 | 1/20 | 0.40 |
| ▸ | CAMK1D | Q8IU85 | 1/20 | 0.40 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20511300 | 1.00 | PIKFYVE (0.61) | PIKFYVEMAPTPOLBATMKDM4E | |
| SCHEMBL20511305 | 1.00 | PIKFYVE (0.61) | PIKFYVEMAPTPOLBATMKDM4E | |
| SCHEMBL20511292 | 0.92 | PIKFYVE (0.55) | PIKFYVEMAPTPOLBATMKDM4E | |
| SCHEMBL20511297 | 0.92 | PIKFYVE (0.55) | PIKFYVEMAPTPOLBATMKDM4E | |
| SCHEMBL31089581 | 0.92 | PIKFYVE (0.55) | PIKFYVEMAPTPOLBATMKDM4E | |
| SCHEMBL31089726 | 0.89 | PIKFYVE (0.76) | PIKFYVEMAPTATMKDM4ELMNA | |
| SCHEMBL20511322 | 0.89 | PIKFYVE (0.76) | PIKFYVEMAPTATMKDM4ELMNA | |
| SCHEMBL20511324 | 0.89 | PIKFYVE (0.76) | PIKFYVEMAPTATMKDM4ELMNA | |
| SCHEMBL20511365 | 0.87 | PIKFYVE (0.61) | PIKFYVEMAPTATMKDM4ELMNA | |
| SCHEMBL20511360 | 0.87 | PIKFYVE (0.61) | PIKFYVEMAPTATMKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240294536-A1 | FUSED TRIAZOLO-PYRIMIDINE COMPOUNDS HAVING USEFUL PHARMACEUTICAL APPLICATION | PIKSCI INC. (CA) | 2024-09-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240294536-A1 | FUSED TRIAZOLO-PYRIMIDINE COMPOUNDS HAVING USEFUL PHARMACEUTICAL APPLICATION | PIKFYVE, PIP4K2B, PIK3CA | PIKFYVE 1/4885MAPT 3840/4885POLB 1258/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.