Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | ASPH | Q12797 | 3/20 | 0.44 |
| ▸ | KDM8 | Q8N371 | 2/20 | 0.44 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.41 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.41 |
| ▸ | P4HTM | Q9NXG6 | 2/20 | 0.39 |
| ▸ | P4HA1 | P13674 | 1/20 | 0.39 |
| ▸ | MIF | P14174 | 1/20 | 0.39 |
| ▸ | KDM6B | O15054 | 1/20 | 0.38 |
| ▸ | TET3 | O43151 | 1/20 | 0.38 |
| ▸ | KDM4A | O75164 | 1/20 | 0.38 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KDM5A | P29375 | 1/20 | 0.38 |
| ▸ | KDM5C | P41229 | 1/20 | 0.38 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.38 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.38 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31513879 | 0.84 | KDM4E (0.47) | KDM4EALDH1A1SMN1; SMN2ASPHKDM8 | |
| SCHEMBL3135116 | 0.81 | KDM4E (0.48) | KDM4EALDH1A1SMN1; SMN2ASPHKDM8 | |
| SCHEMBL31052887 | 0.81 | KDM4E (0.48) | KDM4EALDH1A1SMN1; SMN2ASPHKDM8 | |
| SCHEMBL31052884 | 0.81 | KDM4E (0.48) | KDM4EALDH1A1SMN1; SMN2ASPHKDM8 | |
| SCHEMBL23481999 | 0.78 | MAPK1 (0.50) | KDM4EALDH1A1MAPTGLAGABRP | |
| SCHEMBL8220004 | 0.78 | KDM4E (0.60) | KDM4EALDH1A1SMN1; SMN2ASPHKDM8 | |
| SCHEMBL5917874 | 0.78 | KDM4E (0.46) | KDM4EALDH1A1SMN1; SMN2ASPHKDM8 | |
| SCHEMBL3242847 | 0.78 | KDM4E (0.55) | KDM4EALDH1A1ASPHKDM8P4HTM | |
| SCHEMBL27106805 | 0.78 | KDM4E (0.48) | KDM4EALDH1A1SMN1; SMN2ASPHKDM8 | |
| SCHEMBL21989487 | 0.76 | KDM4E (0.63) | KDM4EALDH1A1SMN1; SMN2ASPHKDM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250051324-A1 | PARP INHIBITOR, PHARMACEUTICAL COMPOSITION COMPRISING SAME, AND USE THEREOF | KEYTHERA (SUZHOU) BIO-PHARMACEUTICALS CO., LIMITED (CN) | 2025-02-13 | — | — | US | disclosed |
| EP-4450498-A1 | PARP INHIBITOR, PHARMACEUTICAL COMPOSITION COMPRISING SAME, AND USE THEREOF | Keythera (Suzhou) Bio-Pharmaceuticals Co., Limited (CN) | 2024-10-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250051324-A1 | PARP INHIBITOR, PHARMACEUTICAL COMPOSITION COMPRISING SAME, AND USE THEREOF | PARP1, PARP2, PARP11 | KDM4E 1035/4885ALDH1A1 901/4885SMN1; SMN2 2317/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.