Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 2/20 | 0.66 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.66 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.66 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | USP2 | O75604 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | HTT | P42858 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31090323 | 0.94 | MAPK8 (0.58) | MAPK8MAPK9MAPK10L3MBTL1GAA | |
| SCHEMBL31090343 | 0.82 | MAPK8 (0.66) | MAPK8MAPK9MAPK10L3MBTL1RAB9A | |
| SCHEMBL10082849 | 0.82 | MAPK8 (0.70) | MAPK8MAPK9MAPK10L3MBTL1RAB9A | |
| SCHEMBL29404340 | 0.82 | MAPK8 (0.70) | MAPK8MAPK9MAPK10L3MBTL1RAB9A | |
| SCHEMBL8045048 | 0.80 | MAPT (0.47) | MAPK8MAPK9MAPK10GAARAB9A | |
| SCHEMBL8049908 | 0.80 | ALDH1A1 (0.47) | MAPK8MAPK9MAPK10GAARAB9A | |
| SCHEMBL8034759 | 0.80 | MAPT (0.47) | MAPK8MAPK9MAPK10GAARAB9A | |
| SCHEMBL8044886 | 0.80 | MAPK8 (0.51) | MAPK8MAPK9MAPK10GAARAB9A | |
| SCHEMBL8046704 | 0.80 | ALDH1A1 (0.60) | MAPK8MAPK9MAPK10L3MBTL1GAA | |
| SCHEMBL31090345 | 0.80 | MAPK8 (0.73) | MAPK8MAPK9MAPK10L3MBTL1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024187093-A1 | ERK INHIBITORS | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2024-09-12 | — | — | WO | disclosed |