Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.40 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.36 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.36 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.36 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.36 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.36 |
| ▸ | IDH1 | O75874 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22350226 | 1.00 | KDM4E (0.45) | KDM4EPOLBLMNAMAPTPARP10 | |
| SCHEMBL4018743 | 0.86 | ACHE (0.41) | KDM4EPOLBLMNAMAPTPARP10 | |
| SCHEMBL30967887 | 0.86 | ACHE (0.41) | KDM4EPOLBLMNAMAPTPARP10 | |
| SCHEMBL7777529 | 0.83 | MAPT (0.64) | KDM4EPOLBLMNAMAPTCYP1A2 | |
| SCHEMBL23813107 | 0.81 | PDE5A (0.39) | CYP1A2ACHEPDE5A | |
| SCHEMBL31124924 | 0.81 | CYP11B1 (0.33) | KDM4EPOLBLMNAMAPTCYP1A2 | |
| SCHEMBL14799640 | 0.81 | CYP11B1 (0.33) | KDM4EPOLBLMNAMAPTCYP1A2 | |
| SCHEMBL30023013 | 0.77 | ACHE (0.50) | KDM4EMAPTCYP1A2ACHEIDH1 | |
| SCHEMBL578148 | 0.77 | ACHE (0.50) | KDM4EMAPTCYP1A2ACHEIDH1 | |
| SCHEMBL5210991 | 0.75 | HTT (0.50) | KDM4EPOLBLMNAMAPTACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113677659-B | Substituted amide compounds useful as farnesoid X receptor modulators | 百时美施贵宝公司 | 2024-09-06 | — | — | CN | disclosed |