Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.52 |
| ▸ | PYGL | P06737 | 10/20 | 0.51 |
| ▸ | F10 | P00742 | 8/20 | 0.50 |
| ▸ | F2 | P00734 | 3/20 | 0.50 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3079242 | 1.00 | SMYD3 (0.52) | SMYD3PYGLF10F2EHMT2 | |
| SCHEMBL3101017 | 0.85 | SMYD3 (0.49) | SMYD3PYGLF10F2EHMT2 | |
| SCHEMBL2939776 | 0.85 | F10 (0.52) | SMYD3PYGLF10EHMT2 | |
| SCHEMBL2941234 | 0.85 | F10 (0.52) | SMYD3PYGLF10EHMT2 | |
| SCHEMBL2941857 | 0.85 | F10 (0.56) | SMYD3F10F2EHMT2 | |
| SCHEMBL6361621 | 0.85 | F10 (0.57) | SMYD3PYGLF10F2 | |
| SCHEMBL2942544 | 0.85 | F10 (0.56) | SMYD3F10F2EHMT2 | |
| SCHEMBL2938409 | 0.83 | EHMT2 (0.49) | SMYD3PYGLF10EHMT2 | |
| SCHEMBL6362844 | 0.82 | F10 (0.55) | SMYD3PYGLF10EHMT2 | |
| SCHEMBL2941142 | 0.82 | PYGL (0.47) | SMYD3PYGLF10EHMT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100093785-A1 | DIAMINE DERIVATIVES | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2010-04-15 | — | — | US | disclosed |
| US-20050245565-A1 | Diamine derivatives | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2005-11-03 | — | — | US | disclosed |
| US-20050119486-A1 | Diamine derivatives | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2005-06-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050245565-A1 | Diamine derivatives | C9, C1S, C1R | SMYD3 3513/4885PYGL 3803/4885F10 196/4885 |
| US-20100093785-A1 | DIAMINE DERIVATIVES | C9, C1S, C1R | SMYD3 3311/4885PYGL 4049/4885F10 72/4885 |
| US-20050119486-A1 | Diamine derivatives | C9, C1S, C1R | SMYD3 3513/4885PYGL 3803/4885F10 196/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.