SCHEMBL31093995

SCHEMBL31093995

Cc1cc(Cl)c([N+](=O)[O-])c(Cl)c1Cl

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.54
TSHR P16473 4/20 0.54
GRIN2D O15399 4/20 0.47
GRIN3B O60391 4/20 0.47
GRIN1 Q05586 4/20 0.47
GRIN2A Q12879 4/20 0.47
GRIN2B Q13224 4/20 0.47
GRIN2C Q14957 4/20 0.47
GRIN3A Q8TCU5 4/20 0.47
TDP1 Q9NUW8 3/20 0.43
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
HSD17B10 Q99714 1/20 0.36
DCTPP1 Q9H773 2/20 0.36
NPC1 O15118 1/20 0.36
LMNA P02545 1/20 0.36
POLB P06746 1/20 0.36
MAPT P10636 1/20 0.36
MAPK1 P28482 1/20 0.36
OPRD1 P41143 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11299940 1.00 ALDH1A1 (0.54) ALDH1A1TSHRGRIN2DGRIN3BGRIN1
SCHEMBL11125778 0.83 TSHR (0.72) ALDH1A1TSHRGRIN2DGRIN3BGRIN1
SCHEMBL10976188 0.83 TSHR (0.59) ALDH1A1TSHRGRIN2DGRIN3BGRIN1
SCHEMBL11049723 0.82 TSHR (0.47) ALDH1A1TSHRGRIN2DGRIN3BGRIN1
SCHEMBL11029357 0.82 TSHR (0.52) ALDH1A1TSHRGRIN2DGRIN3BGRIN1
SCHEMBL5921857 0.80 TSHR (0.74) ALDH1A1TSHRGRIN2DGRIN3BGRIN1
SCHEMBL5042912 0.80 TSHR (0.73) ALDH1A1TSHRGRIN2DGRIN3BGRIN1
SCHEMBL6579700 0.79 ALDH1A1 (0.54) ALDH1A1TSHRGRIN2DGRIN3BGRIN1
SCHEMBL11049733 0.79 TSHR (0.65) ALDH1A1TSHRGRIN2DGRIN3BGRIN1
SCHEMBL38663877 0.79 TSHR (0.65) ALDH1A1TSHRGRIN2DGRIN3BGRIN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118561708-A Benzoyl bacteria method for synthesizing amine 湖北晟康化工有限公司 2024-08-30 CN claimed
CN-118561708-A Benzoyl bacteria method for synthesizing amine 湖北晟康化工有限公司 2024-08-30 CN disclosed