Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.57 |
| ▸ | POLB | P06746 | 4/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GALR3 | O60755 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.38 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25220823 | 0.81 | MAPK14 (0.52) | MAPTPOLBMEN1KMT2AALDH1A1 | |
| SCHEMBL4772911 | 0.80 | PDGFRB (0.44) | MAPTTDP1POLBMEN1KMT2A | |
| SCHEMBL9913556 | 0.79 | MAPT (0.72) | MAPTTDP1POLBMEN1KMT2A | |
| SCHEMBL22832713 | 0.77 | MAPK14 (0.50) | MAPTMEN1KMT2AALDH1A1TSHR | |
| SCHEMBL17736221 | 0.77 | TDP1 (0.60) | MAPTTDP1POLBMEN1KMT2A | |
| SCHEMBL31118563 | 0.76 | MAPK14 (0.40) | MAPTPOLBMEN1KMT2AALDH1A1 | |
| SCHEMBL5817998 | 0.75 | TDP1 (0.57) | MAPTTDP1POLBMEN1KMT2A | |
| SCHEMBL14720958 | 0.75 | BACE1 (0.42) | ALDH1A1MAPK14BACE1IKBKETBK1 | |
| SCHEMBL23092185 | 0.75 | BACE1 (0.42) | MAPK14BACE1IKBKETBK1HTR1D | |
| SCHEMBL23105031 | 0.75 | BACE1 (0.42) | BACE1IKBKETBK1HTR1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024208228-A1 | NOVEL COMPOUNDS, COMPOSITIONS COMPRISING THE SAME AND USES THEREOF | NUPHASE THERAPEUTICS (HANGZHOU) LIMITED., CO. (CN) | 2024-10-10 | — | — | WO | disclosed |