Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.65 |
| ▸ | POLB | P06746 | 2/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 4/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | CISD2 | Q8N5K1 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | CASP7 | P55210 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CFTR | P13569 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20589795 | 1.00 | KDM4E (0.65) | KDM4EPOLBHSD17B10USP2GAA | |
| SCHEMBL3361544 | 0.84 | ALDH1A1 (0.61) | KDM4EPOLBHSD17B10HPGDALDH1A1 | |
| SCHEMBL20588519 | 0.84 | KDM4E (0.49) | KDM4EPOLBGAAHPGDALDH1A1 | |
| SCHEMBL31095392 | 0.84 | ALDH1A1 (0.61) | KDM4EPOLBHSD17B10HPGDALDH1A1 | |
| SCHEMBL31095381 | 0.84 | KDM4E (0.49) | KDM4EPOLBGAAHPGDALDH1A1 | |
| SCHEMBL25218326 | 0.84 | KDM4E (0.49) | KDM4EPOLBGAAALDH1A1MAPT | |
| SCHEMBL31095594 | 0.84 | KDM4E (0.49) | KDM4EPOLBGAAALDH1A1MAPT | |
| SCHEMBL1361427 | 0.82 | KDM4E (0.51) | KDM4EPOLBHSD17B10USP2GAA | |
| SCHEMBL30689849 | 0.82 | KDM4E (0.56) | KDM4EPOLBHSD17B10USP2GAA | |
| Hydrochloric Acid SCHEMBL27514522 | 0.82 | ALDH1A1 (0.59) | KDM4EPOLBHSD17B10USP2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119060060-A | Imidazole-containing ALK2 kinase inhibitors | 拜奥克里斯特制药公司 | 2024-12-03 | — | — | CN | disclosed |
| CN-110913855-B | Imidazole-containing ALK2 kinase inhibitors | 拜奥克里斯特制药公司 | 2024-09-03 | — | — | CN | disclosed |