Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD1 | Q15116 | 2/20 | 0.33 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.33 |
| ▸ | MAPK13 | O15264 | 11/20 | 0.32 |
| ▸ | DRD1 | P21728 | 3/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | DRD4 | P21917 | 1/20 | 0.32 |
| ▸ | DRD5 | P21918 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | PRKDC | P78527 | 1/20 | 0.31 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31095973 | 0.94 | MAPK13 (0.35) | MAPK13MAPK14GRM2 | |
| SCHEMBL31095965 | 0.89 | MAPK13 (0.37) | PDCD1CD274MAPK13DRD1MAPK14 | |
| SCHEMBL31096158 | 0.85 | GRM2 (0.33) | MAPK13DRD1DRD2DRD4DRD5 | |
| SCHEMBL31096130 | 0.84 | ABL1 (0.41) | PDCD1CD274MAPK13DRD1MAPK14 | |
| SCHEMBL31145842 | 0.81 | CD274 (0.45) | PDCD1CD274 | |
| SCHEMBL31096067 | 0.78 | CCNB2 (0.38) | PDCD1CD274MAPK13MAPK14 | |
| SCHEMBL31095986 | 0.76 | DYRK1B (0.42) | MAPK13DRD1MAPK14DRD2DRD4 | |
| SCHEMBL31096119 | 0.75 | FLT3 (0.59) | — | |
| SCHEMBL31095831 | 0.72 | PDCD1 (0.34) | PDCD1CD274DRD1 | |
| SCHEMBL23725576 | 0.72 | FLT3 (0.33) | CD274 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4434987-A1 | NOVEL PD-L1 INHIBITORS | Affirma Biotech S. L. (ES) | 2024-09-25 | — | — | EP | disclosed |