Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1B | Q9Y463 | 2/20 | 0.42 |
| ▸ | ABL1 | P00519 | 1/20 | 0.42 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.42 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.42 |
| ▸ | CDK7 | P50613 | 1/20 | 0.42 |
| ▸ | BTK | Q06187 | 1/20 | 0.42 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.42 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.42 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MAPK13 | O15264 | 4/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.34 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
| ▸ | TNKS | O95271 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | DRD1 | P21728 | 3/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31096158 | 0.88 | GRM2 (0.33) | DYRK1BABL1PDGFRACSNK1A1CDK7 | |
| SCHEMBL31095965 | 0.86 | MAPK13 (0.37) | DYRK1BABL1PDGFRACSNK1A1CDK7 | |
| SCHEMBL31096130 | 0.84 | ABL1 (0.41) | DYRK1BABL1PDGFRACSNK1A1CDK7 | |
| SCHEMBL31095944 | 0.82 | KDM4E (0.49) | DYRK1BABL1PDGFRACSNK1A1CDK7 | |
| SCHEMBL31095927 | 0.79 | CD274 (0.48) | — | |
| SCHEMBL31096010 | 0.76 | PDCD1 (0.33) | MAPK13MAPK14GRM2DRD1DRD2 | |
| SCHEMBL23725576 | 0.74 | FLT3 (0.33) | DYRK1BKDM4EALDH1A1GAADYRK3 | |
| SCHEMBL31095921 | 0.72 | CD274 (0.45) | — | |
| SCHEMBL23725819 | 0.72 | ALDH1A1 (0.36) | KDM4EALDH1A1GAAL3MBTL1GLA | |
| SCHEMBL31096207 | 0.72 | CD274 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4434987-A1 | NOVEL PD-L1 INHIBITORS | Affirma Biotech S. L. (ES) | 2024-09-25 | — | — | EP | disclosed |