Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNK3 | O14649 | 6/20 | 0.48 |
| ▸ | KCNK9 | Q9NPC2 | 6/20 | 0.48 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.47 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | JAK1 | P23458 | 2/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
| ▸ | PREP | P48147 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18418205 | 0.89 | KCNK3 (0.48) | KCNK3KCNK9HSD11B1CHRM2CHRM1 | |
| SCHEMBL23053901 | 0.88 | KCNK3 (0.52) | KCNK3KCNK9HSD11B1CHRM2CHRM1 | |
| SCHEMBL22569544 | 0.88 | KCNK3 (0.52) | KCNK3KCNK9HSD11B1CHRM2CHRM1 | |
| SCHEMBL3538916 | 0.88 | KCNK3 (0.52) | KCNK3KCNK9HSD11B1CHRM2CHRM1 | |
| SCHEMBL31096238 | 0.86 | GPR119 (0.42) | KCNK3KCNK9HSD11B1GPR119TP53 | |
| SCHEMBL16627095 | 0.85 | AR (0.47) | KCNK3KCNK9HSD11B1CHRM2CHRM1 | |
| SCHEMBL2301209 | 0.84 | KMT2A (0.55) | KCNK3KCNK9HSD11B1CHRM2CHRM1 | |
| SCHEMBL24699088 | 0.81 | KDM4E (0.47) | HSD11B1GPR119 | |
| SCHEMBL29914114 | 0.81 | KDM4E (0.47) | HSD11B1GPR119 | |
| SCHEMBL29138572 | 0.81 | KDM4E (0.47) | HSD11B1GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113521299-B | Pyrazolopyrimidine derivative or conjugate thereof, preparation method and application thereof | 江苏恒瑞医药股份有限公司 | 2024-07-16 | — | — | CN | disclosed |