Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | PKM | P14618 | 2/20 | 0.52 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 4/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | KDM6B | O15054 | 1/20 | 0.43 |
| ▸ | KDM4A | O75164 | 1/20 | 0.43 |
| ▸ | KDM5C | P41229 | 1/20 | 0.43 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.43 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.43 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CCR1 | P32246 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23202468 | 1.00 | KDM4E (0.52) | KDM4EMEN1KMT2AALDH1A1PKM | |
| SCHEMBL23202504 | 0.88 | KDM4E (0.47) | KDM4EMEN1KMT2AALDH1A1PKM | |
| SCHEMBL31096548 | 0.88 | KDM4E (0.47) | KDM4EMEN1KMT2AALDH1A1PKM | |
| SCHEMBL31096525 | 0.85 | KDM4E (0.69) | KDM4EMEN1KMT2AALDH1A1PKM | |
| SCHEMBL23202557 | 0.85 | KDM4E (0.69) | KDM4EMEN1KMT2AALDH1A1PKM | |
| SCHEMBL23479904 | 0.85 | HTT (0.47) | KDM4EMEN1KMT2AALDH1A1PKM | |
| SCHEMBL31096541 | 0.85 | KDM4E (0.53) | KDM4EMEN1KMT2AALDH1A1PKM | |
| SCHEMBL23202481 | 0.85 | HTT (0.53) | KDM4EMEN1KMT2AALDH1A1PKM | |
| SCHEMBL23202617 | 0.85 | KDM4E (0.53) | KDM4EMEN1KMT2AALDH1A1PKM | |
| SCHEMBL23202494 | 0.84 | KDM4E (0.57) | KDM4EMEN1KMT2AALDH1A1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112533601-B | EAAT2 activators and methods of use thereof | 俄亥俄州创新基金会 | 2024-08-16 | — | — | CN | disclosed |