Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | AURKA | O14965 | 1/20 | 0.32 |
| ▸ | SYK | P43405 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31097398 | 1.00 | LRRK2 (0.35) | LRRK2DYRK1AALOX15SRCKDM4E | |
| SCHEMBL22032490 | 0.79 | DYRK1A (0.41) | LRRK2DYRK1AALOX15SRCKDM4E | |
| SCHEMBL31097394 | 0.73 | DYRK1A (0.37) | DYRK1AKDM4EALDH1A1 | |
| SCHEMBL21782770 | 0.73 | DYRK1A (0.37) | DYRK1AKDM4EALDH1A1 | |
| SCHEMBL3606665 | 0.73 | NEK1 (0.34) | DYRK1A | |
| SCHEMBL31097393 | 0.73 | DYRK1A (0.37) | DYRK1AKDM4EALDH1A1 | |
| SCHEMBL31674353 | 0.72 | AURKA (0.37) | LRRK2DYRK1AALOX15KDM4EALDH1A1 | |
| SCHEMBL3998036 | 0.72 | AURKA (0.37) | LRRK2DYRK1AALOX15KDM4EALDH1A1 | |
| SCHEMBL2710842 | 0.72 | ALDH1A1 (0.43) | LRRK2KDM4EALDH1A1SYK | |
| SCHEMBL19631236 | 0.71 | NEK1 (0.37) | DYRK1AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118580252-A | PROTAC compound, pharmaceutical composition containing same, and preparation method and application thereof | 百极弘烨(南通)医药科技有限公司 | 2024-09-03 | — | — | CN | disclosed |