Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 3/20 | 0.43 |
| ▸ | NFATC1 | O95644 | 2/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.43 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | CHUK | O15111 | 4/20 | 0.42 |
| ▸ | PIM1 | P11309 | 2/20 | 0.42 |
| ▸ | IDO1 | P14902 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GABRP | O00591 | 1/20 | 0.42 |
| ▸ | GABRD | O14764 | 1/20 | 0.42 |
| ▸ | IKBKB | O14920 | 1/20 | 0.42 |
| ▸ | AURKA | O14965 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TOP1 | P11387 | 1/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.42 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1344802 | 1.00 | DYRK1A (0.43) | DYRK1ANFATC1ADORA2AADORA2BGSK3B | |
| SCHEMBL254869 | 0.83 | ACHE (0.46) | DYRK1AADORA2AADORA2BPIM1IDO1 | |
| SCHEMBL30270020 | 0.77 | PDPK1 (0.55) | DYRK1ANFATC1GSK3BCHUKPIM1 | |
| SCHEMBL868303 | 0.77 | PDPK1 (0.55) | DYRK1ANFATC1GSK3BCHUKPIM1 | |
| SCHEMBL25945842 | 0.76 | LATS1 (0.42) | DYRK1ANFATC1GSK3BADORA3CHUK | |
| SCHEMBL31097608 | 0.75 | DYRK1A (0.43) | DYRK1ANFATC1GSK3BADORA3CHUK | |
| SCHEMBL12311284 | 0.75 | DYRK1A (0.43) | DYRK1ANFATC1GSK3BADORA3CHUK | |
| SCHEMBL658647 | 0.75 | CHUK (0.44) | DYRK1ANFATC1ADORA2AGSK3BADORA3 | |
| SCHEMBL1344801 | 0.75 | CHUK (0.42) | DYRK1ANFATC1ADORA2AGSK3BADORA3 | |
| SCHEMBL31346280 | 0.75 | CHUK (0.44) | DYRK1ANFATC1GSK3BCHUKPIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118765278-A | Indazole compounds and pharmaceutical uses thereof | 日本烟草产业株式会社 | 2024-10-11 | — | — | CN | disclosed |