Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.35 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NAMPT | P43490 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.31 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30484976 | 0.82 | NR1H2 (0.41) | NR1H2PDE4BUSP30USP2SMN1; SMN2 | |
| SCHEMBL30484975 | 0.82 | NR1H2 (0.41) | NR1H2PDE4BUSP30USP2SMN1; SMN2 | |
| SCHEMBL26093056 | 0.81 | NR1H2 (0.50) | NR1H2USP2SMN1; SMN2NAMPTMEN1 | |
| SCHEMBL13110458 | 0.79 | NR1H2 (0.48) | NR1H2PDE4BUSP30USP2SMN1; SMN2 | |
| SCHEMBL21216437 | 0.79 | NR1H2 (0.55) | NR1H2PDE4BUSP30USP2SMN1; SMN2 | |
| SCHEMBL29827071 | 0.79 | NR1H2 (0.55) | NR1H2PDE4BUSP30USP2SMN1; SMN2 | |
| SCHEMBL30837088 | 0.79 | NR1H2 (0.48) | NR1H2PDE4BUSP30USP2SMN1; SMN2 | |
| SCHEMBL14801400 | 0.79 | NR1H2 (0.55) | NR1H2PDE4BUSP30USP2SMN1; SMN2 | |
| SCHEMBL29826963 | 0.79 | NR1H2 (0.55) | NR1H2PDE4BUSP30USP2SMN1; SMN2 | |
| SCHEMBL26906071 | 0.79 | NR1H2 (0.55) | NR1H2PDE4BUSP30USP2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118632841-A | Heterocyclic compounds for the treatment of cancer | 阿提奥斯医药有限公司 | 2024-09-10 | — | — | CN | disclosed |