Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 2/20 | 0.50 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | AKT1 | P31749 | 1/20 | 0.41 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | METAP1 | P53582 | 1/20 | 0.40 |
| ▸ | KDM4A | O75164 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RPS6KA1 | Q15418 | 1/20 | 0.39 |
| ▸ | TDP2 | O95551 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6756990 | 0.90 | KCNA5 (0.49) | BRD4NAMPTL3MBTL1AKT1KCNA5 | |
| SCHEMBL16767053 | 0.85 | KDM4E (0.50) | NAMPTL3MBTL1AKT1KCNA5MAPT | |
| SCHEMBL29883701 | 0.85 | KDM4E (0.50) | NAMPTL3MBTL1AKT1KCNA5MAPT | |
| SCHEMBL29435339 | 0.81 | LMNA (0.52) | NAMPTL3MBTL1KCNA5KDM4ALMNA | |
| SCHEMBL20428076 | 0.81 | LMNA (0.52) | NAMPTL3MBTL1KCNA5KDM4ALMNA | |
| SCHEMBL4906896 | 0.80 | BRD4 (0.70) | BRD4MAPTMETAP1LMNANPC1 | |
| SCHEMBL16829010 | 0.80 | NAMPT (0.45) | BRD4NAMPTL3MBTL1AKT1KCNA5 | |
| SCHEMBL12578946 | 0.79 | ATR (0.47) | NAMPTL3MBTL1AKT1KCNA5KDM4E | |
| SCHEMBL15804093 | 0.79 | NAMPT (0.46) | BRD4NAMPTL3MBTL1AKT1KCNA5 | |
| SCHEMBL28472394 | 0.78 | BRD4 (0.61) | BRD4MAPTKDM4ELMNANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113563245-B | Substituted pyrrolidines and their use in medicine | 广东东阳光药业股份有限公司 | 2024-10-15 | — | — | CN | disclosed |