Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | PIK3C3 | Q8NEB9 | 4/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.45 |
| ▸ | NPC1 | O15118 | 4/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.42 |
| ▸ | HSD17B14 | Q9BPX1 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31098672 | 0.80 | GAA (0.52) | GAAHSD17B10NPC1RAB9ATP53 | |
| SCHEMBL10415053 | 0.79 | GAA (0.49) | GAAHSD17B10NPC1RAB9ATP53 | |
| SCHEMBL10416912 | 0.78 | GAA (0.51) | GAAHSD17B10NPC1RAB9ATP53 | |
| SCHEMBL30739730 | 0.78 | MAPT (0.47) | PIK3C3MAPTPIK3CAGRM1 | |
| SCHEMBL31098583 | 0.72 | GAA (0.57) | GAAHSD17B10NPC1RAB9ATP53 | |
| SCHEMBL18765244 | 0.72 | GAA (0.57) | GAAHSD17B10NPC1RAB9ATP53 | |
| SCHEMBL3391124 | 0.72 | GAA (0.48) | GAAHSD17B10NPC1RAB9ATP53 | |
| SCHEMBL2096358 | 0.72 | HTT (0.46) | PIK3C3NPC1RAB9AMAPTPIK3CA | |
| SCHEMBL7002940 | 0.72 | FSCN1 (0.49) | PIK3C3MAPTPIK3CAALDH1A1L3MBTL1 | |
| SCHEMBL2096355 | 0.72 | HTT (0.46) | PIK3C3MAPTPIK3CAALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113563245-B | Substituted pyrrolidines and their use in medicine | 广东东阳光药业股份有限公司 | 2024-10-15 | — | — | CN | disclosed |