SCHEMBL30739730

SCHEMBL30739730

CN(C(=O)c1ccccc1)c1ccc(F)cc1F

nearest known ligand 0.47

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.47
PIK3CA P42336 1/20 0.46
SIRT2 Q8IXJ6 2/20 0.45
TACR1 P25103 1/20 0.45
GPBAR1 Q8TDU6 2/20 0.43
NR1H2 P55055 1/20 0.42
NR1H3 Q13133 1/20 0.42
NR3C2 P08235 1/20 0.42
RECQL P46063 1/20 0.42
KDM4E B2RXH2 1/20 0.41
KMT2A Q03164 1/20 0.41
PIK3C3 Q8NEB9 1/20 0.41
ABCB1 P08183 1/20 0.41
ABCC1 P33527 1/20 0.41
HDAC1 Q13547 1/20 0.41
OPRM1 P35372 1/20 0.41
OPRL1 P41146 1/20 0.41
HTT P42858 1/20 0.41
GRM1 Q13255 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9339071 0.81 MLYCD (0.47) NR3C2RECQLHDAC1OPRM1OPRL1
SCHEMBL2096358 0.81 HTT (0.46) MAPTPIK3CAKMT2APIK3C3HTT
SCHEMBL31098541 0.78 GAA (0.48) MAPTPIK3CAPIK3C3GRM1
SCHEMBL2096355 0.78 HTT (0.46) MAPTPIK3CAKMT2APIK3C3HTT
SCHEMBL7002940 0.78 FSCN1 (0.49) MAPTPIK3CAKMT2APIK3C3HTT
SCHEMBL9001643 0.77 KMT2A (0.53) NR1H2NR1H3RECQLKDM4EKMT2A
SCHEMBL5317201 0.76 HTT (0.49) MAPTPIK3CAKMT2APIK3C3HTT
SCHEMBL30369800 0.76 NR1H3 (0.62) MAPTGPBAR1NR1H2NR1H3NR3C2
SCHEMBL27447806 0.75 KMT2A (0.54) PIK3CAGPBAR1NR1H2NR1H3KDM4E
SCHEMBL5647030 0.74 KMT2A (0.58) KMT2AHDAC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118044519-A Molecules having pesticidal utility, and intermediates, compositions and methods related thereto 科迪华农业科技有限责任公司 2024-05-17 CN disclosed
CN-110072842-B Molecules having pesticidal utility, and intermediates, compositions and methods related thereto 科迪华农业科技有限责任公司 2024-02-02 CN disclosed