Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 8/20 | 0.63 |
| ▸ | HTR2A | P28223 | 4/20 | 0.48 |
| ▸ | HTR2C | P28335 | 4/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.40 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.40 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | AGXT | P21549 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12068165 | 0.86 | RIPK1 (0.47) | RIPK1HTR2AHTR2CSLC6A4CACNA1G | |
| SCHEMBL31137753 | 0.86 | RIPK1 (0.47) | RIPK1HTR2AHTR2CSLC6A4CACNA1G | |
| SCHEMBL30512182 | 0.86 | RIPK1 (0.50) | RIPK1HTR2AHTR2CSLC6A4CACNA1G | |
| SCHEMBL21494224 | 0.86 | RIPK1 (0.50) | RIPK1HTR2AHTR2CSLC6A4CACNA1G | |
| SCHEMBL23105683 | 0.84 | RIPK1 (0.49) | RIPK1HTR2AHTR2CSLC6A4CACNA1G | |
| SCHEMBL23105681 | 0.83 | RIPK1 (0.48) | RIPK1HTR2AHTR2CSLC6A4CACNA1G | |
| SCHEMBL14762235 | 0.81 | SSTR4 (0.52) | RIPK1HTR2AHTR2CSLC6A4MAOB | |
| SCHEMBL5912672 | 0.81 | RIPK1 (0.43) | RIPK1HTR2AHTR2CSLC6A4CACNA1G | |
| SCHEMBL31118082 | 0.80 | RIPK1 (0.47) | RIPK1HTR2AHTR2CSLC6A4MAOB | |
| SCHEMBL506105 | 0.80 | RIPK1 (0.40) | RIPK1HTR2AHTR2CSLC6A4CACNA1G |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113563245-B | Substituted pyrrolidines and their use in medicine | 广东东阳光药业股份有限公司 | 2024-10-15 | — | — | CN | disclosed |