SCHEMBL31098640

SCHEMBL31098640

CSCCNC(=O)c1ccc(-c2cccc(C(F)(F)F)c2)o1

nearest known ligand 0.64

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.64
CYP2C19 P33261 1/20 0.64
KMT2A Q03164 3/20 0.55
KDM4E B2RXH2 3/20 0.55
HPGD P15428 2/20 0.55
SMN1; SMN2 Q16637 2/20 0.55
ALDH1A1 P00352 3/20 0.55
MEN1 O00255 2/20 0.55
HSD17B10 Q99714 1/20 0.55
TDP1 Q9NUW8 1/20 0.55
SLC9A1 P19634 1/20 0.53
LMNA P02545 1/20 0.48
CTSS P25774 1/20 0.47
FNTA P49354 1/20 0.46
FNTB P49356 1/20 0.46
CHRNA7 P36544 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31098669 0.94 CYP1A2 (0.61) CYP1A2CYP2C19KMT2AKDM4EHPGD
SCHEMBL31098658 0.89 CYP1A2 (0.61) CYP1A2CYP2C19KMT2AKDM4EHPGD
SCHEMBL9877550 0.81 CYP1A2 (0.71) CYP1A2CYP2C19KMT2AKDM4EHPGD
SCHEMBL8338146 0.81 CYP1A2 (0.64) CYP1A2CYP2C19KMT2AKDM4EHPGD
SCHEMBL12563573 0.79 CYP1A2 (0.62) CYP1A2CYP2C19KMT2AKDM4EHPGD
Trifluoromethanesulfonic Acid SCHEMBL31098650 0.79 CYP1A2 (0.56) CYP1A2CYP2C19KMT2AKDM4EHPGD
SCHEMBL12563571 0.78 CYP1A2 (0.61) CYP1A2CYP2C19KMT2AKDM4EHPGD
SCHEMBL12563583 0.78 CYP1A2 (0.60) CYP1A2CYP2C19KMT2AKDM4EHPGD
Trifluoromethanesulfonic Acid SCHEMBL31098733 0.77 CYP1A2 (0.54) CYP1A2CYP2C19KMT2AKDM4EHPGD
Trifluoromethanesulfonic Acid SCHEMBL31098654 0.77 CYP1A2 (0.54) CYP1A2CYP2C19KMT2AKDM4EHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024196978-A2 SULFONIUM COMPOUNDS AND METHODS FOR MAKING AND USING THE SAME UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2024-09-26 WO disclosed