Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.71 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.71 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | HPGD | P15428 | 2/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | GAA | P10253 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8338146 | 0.86 | CYP1A2 (0.64) | CYP1A2CYP2C19SLC9A1KDM4EKMT2A | |
| SCHEMBL5842720 | 0.85 | SLC9A1 (0.74) | CYP1A2CYP2C19SLC9A1KDM4EKMT2A | |
| SCHEMBL1222870 | 0.83 | SLC9A1 (0.67) | CYP1A2CYP2C19SLC9A1KDM4EKMT2A | |
| SCHEMBL1199181 | 0.82 | CYP1A2 (0.77) | CYP1A2CYP2C19SLC9A1KDM4EKMT2A | |
| SCHEMBL3326658 | 0.82 | SLC9A1 (0.66) | CYP1A2CYP2C19SLC9A1KDM4EKMT2A | |
| SCHEMBL11806267 | 0.82 | CYP1A2 (0.68) | CYP1A2CYP2C19SLC9A1KDM4EKMT2A | |
| SCHEMBL11159190 | 0.81 | CYP1A2 (0.67) | CYP1A2CYP2C19SLC9A1KDM4EKMT2A | |
| SCHEMBL31098640 | 0.81 | CYP1A2 (0.64) | CYP1A2CYP2C19SLC9A1KDM4EKMT2A | |
| SCHEMBL12563573 | 0.80 | CYP1A2 (0.62) | CYP1A2CYP2C19SLC9A1KDM4EKMT2A | |
| SCHEMBL4944695 | 0.80 | CYP1A2 (0.62) | CYP1A2CYP2C19SLC9A1KDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5023272-A | Use of 5-phenyl-2-furan esters and amides as antiepileptic agents | NORWICH EATON PHARMACEUTICALS, INC. (US) | 1991-06-11 | — | — | US | disclosed |
| EP-0404231-A1 | The use of 5-phenyl-2 furan esters and amides as antiepileptic agents | Norwich Eaton Pharmaceuticals, Inc. (US) | 1990-12-27 | — | — | EP | disclosed |
| US-4403097-A | 5-(3-Trifluoromethylphenyl)-2-furancarboxylic acid 2-(1-methylethylidene)hydrazide | NORWICH EATON PHARMACEUTICALS, INC. (US) | 1983-09-06 | — | — | US | disclosed |