Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 2/20 | 0.47 |
| ▸ | CSF1R | P07333 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | APAF1 | O14727 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | CASP6 | P55212 | 1/20 | 0.44 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.44 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CRHBP | P24387 | 1/20 | 0.42 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | F12 | P00748 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13432673 | 0.86 | KMT2A (0.48) | EGFRCSF1RKDM4ENPC1HPGD | |
| SCHEMBL16484700 | 0.84 | PLAU (0.47) | KDM4ENPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL31098956 | 0.84 | PLAU (0.47) | KDM4ENPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL31098991 | 0.83 | CYP2A6 (0.40) | KDM4ENPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL31098981 | 0.81 | LMNA (0.39) | KDM4ENPC1RAB9AALDH1A1CYP2A6 | |
| SCHEMBL31098978 | 0.81 | KDM4E (0.41) | KDM4ENPC1HPGDRAB9AALDH1A1 | |
| SCHEMBL13250580 | 0.80 | PLAU (0.43) | KDM4ENPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL4270947 | 0.80 | CYP2A6 (0.50) | HPGDSMN1; SMN2ALDH1A1CYP2A6MAPT | |
| SCHEMBL13250582 | 0.79 | PLAU (0.42) | KDM4ENPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL12934730 | 0.78 | CYP2A6 (0.48) | NPC1RAB9ASMN1; SMN2ALDH1A1CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112390755-B | Heteroaryl method for amine | 中国科学院理化技术研究所 | 2024-08-02 | — | — | CN | claimed |