Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 5/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | IDH1 | O75874 | 2/20 | 0.39 |
| ▸ | IDH2 | P48735 | 1/20 | 0.39 |
| ▸ | ACACB | O00763 | 5/20 | 0.38 |
| ▸ | MC4R | P32245 | 4/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.36 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31099041 | 0.88 | MC4R (0.41) | RORCCYP11B2ACACBMC4RESR2 | |
| SCHEMBL24853354 | 0.87 | ACACB (0.42) | CYP11B2ACACBMC4RESR2NR1H2 | |
| SCHEMBL24094546 | 0.87 | ACACB (0.42) | CYP11B2ACACBMC4RESR2NR1H2 | |
| SCHEMBL24094541 | 0.87 | ACACB (0.42) | CYP11B2ACACBMC4RESR2NR1H2 | |
| SCHEMBL31099087 | 0.84 | CYP11B2 (0.39) | CYP11B2ACACBMC4RESR2NR1H2 | |
| SCHEMBL31207242 | 0.82 | MC4R (0.39) | RORCCYP11B2ACACBMC4R | |
| SCHEMBL31099044 | 0.82 | MC4R (0.39) | CYP11B2ACACBMC4R | |
| SCHEMBL31099078 | 0.82 | MC4R (0.39) | RORCCYP11B2ACACBMC4R | |
| SCHEMBL31099100 | 0.79 | MC4R (0.41) | CYP11B2ACACBMC4R | |
| SCHEMBL31099106 | 0.79 | MC4R (0.49) | ACACBMC4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024255412-A1 | SPIRO HETEROCYCLIC COMPOUND AND USE THEREOF | 广州必贝特医药股份有限公司 | 2024-12-19 | — | — | WO | disclosed |
| CN-118510780-A | Spiro heterocyclic compounds and uses thereof | 广州必贝特医药股份有限公司 | 2024-08-16 | — | — | CN | disclosed |