Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL6 | P41182 | 3/20 | 0.41 |
| ▸ | BCOR | Q6W2J9 | 3/20 | 0.41 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 5/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.37 |
| ▸ | HTR2A | P28223 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.36 |
| ▸ | HTR3B | O95264 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | HTR1D | P28221 | 1/20 | 0.36 |
| ▸ | HTR1B | P28222 | 1/20 | 0.36 |
| ▸ | HTR1E | P28566 | 1/20 | 0.36 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.36 |
| ▸ | OXTR | P30559 | 1/20 | 0.36 |
| ▸ | HTR1F | P30939 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL83015 | 0.68 | HRH1 (0.54) | SMN1; SMN2HTR1A | |
| SCHEMBL29874183 | 0.67 | BCL6 (0.84) | BCL6BCORSMN1; SMN2 | |
| SCHEMBL23249972 | 0.67 | BCL6 (0.84) | BCL6BCORSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL70340 | 0.67 | HRH1 (0.53) | SMN1; SMN2HTR1A | |
| SCHEMBL3973922 | 0.64 | UTS2R (0.52) | UTS2RMAPTSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL17304048 | 0.62 | BCL6 (0.44) | BCL6BCORMAPTSMN1; SMN2KMT2A | |
| SCHEMBL17154906 | 0.62 | SLC6A2 (0.49) | HTR1A | |
| SCHEMBL22493009 | 0.61 | ALDH1A1 (0.56) | MAPTSMN1; SMN2DRD3KMT2AMEN1 | |
| SCHEMBL29510718 | 0.61 | ALDH1A1 (0.56) | MAPTSMN1; SMN2DRD3KMT2AMEN1 | |
| SCHEMBL82955 | 0.61 | HRH1 (0.62) | HTR2CKCNH2HTR2AHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119019369-A | Bifunctional molecules comprising an E3 ubiquitin ligase binding moiety linked to a BCL6 targeting moiety | 阿尔维纳斯运营股份有限公司 | 2024-11-26 | — | — | CN | disclosed |
| CN-115397821-B | Bifunctional molecules comprising an E3 ubiquitin ligase binding moiety linked to a BCL6 targeting moiety | 阿尔维纳斯运营股份有限公司 | 2024-09-03 | — | — | CN | disclosed |