Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.58 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13753811 | 0.86 | ALDH1A1 (0.74) | MAPK1ALDH1A1ALOX12KMT2AMEN1 | |
| SCHEMBL11740426 | 0.84 | MAPK1 (0.62) | MAPK1ALDH1A1ALOX12KMT2AMEN1 | |
| SCHEMBL28587970 | 0.84 | MAPK1 (0.62) | MAPK1ALDH1A1ALOX12KMT2AMEN1 | |
| SCHEMBL11877765 | 0.81 | GRN (0.62) | MAPK1ALDH1A1ALOX12KMT2AMEN1 | |
| SCHEMBL6137929 | 0.80 | HTT (0.59) | KMT2AMEN1 | |
| SCHEMBL27601811 | 0.80 | MAPK1 (0.61) | MAPK1ALDH1A1ALOX12KMT2AMEN1 | |
| SCHEMBL27601810 | 0.80 | MAPK1 (0.61) | MAPK1ALDH1A1ALOX12KMT2AMEN1 | |
| SCHEMBL6137933 | 0.80 | HTT (0.59) | KMT2AMEN1 | |
| SCHEMBL11874569 | 0.80 | MAPK1 (0.68) | MAPK1ALDH1A1ALOX12KMT2AMEN1 | |
| SCHEMBL11874584 | 0.80 | MAPK1 (0.68) | MAPK1ALDH1A1ALOX12KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118598771-A | Oral small molecule P-selectin inhibitor, and preparation method and application thereof | 首都医科大学 | 2024-09-06 | — | — | CN | claimed |
| CN-118598771-A | Oral small molecule P-selectin inhibitor, and preparation method and application thereof | 首都医科大学 | 2024-09-06 | — | — | CN | disclosed |