Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 13/20 | 0.42 |
| ▸ | DDB1 | Q16531 | 9/20 | 0.42 |
| ▸ | IKZF3 | Q9UKT9 | 10/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.41 |
| ▸ | PBRM1 | Q86U86 | 7/20 | 0.40 |
| ▸ | SMARCA2 | P51531 | 5/20 | 0.40 |
| ▸ | SMARCA4 | P51532 | 5/20 | 0.40 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31101034 | 0.90 | PBRM1 (0.51) | CRBNDDB1PBRM1SMARCA2SMARCA4 | |
| SCHEMBL31102355 | 0.88 | SMARCA2 (0.36) | CRBNDDB1PBRM1SMARCA2SMARCA4 | |
| SCHEMBL31101071 | 0.85 | PBRM1 (0.41) | CRBNDDB1IKZF3DRD2ADRA1D | |
| SCHEMBL31102039 | 0.83 | PBRM1 (0.49) | CRBNDDB1PBRM1SMARCA2SMARCA4 | |
| SCHEMBL31101716 | 0.82 | PBRM1 (0.47) | CRBNDDB1IKZF3DRD2ADRA1D | |
| SCHEMBL31099599 | 0.82 | CRBN (0.54) | CRBNDDB1IKZF3DRD2ADRA1D | |
| SCHEMBL31101161 | 0.80 | SMARCA2 (0.39) | CRBNDDB1IKZF3DRD2ADRA1D | |
| SCHEMBL31101374 | 0.80 | DDB1 (0.38) | CRBNDDB1PBRM1SMARCA2SMARCA4 | |
| SCHEMBL31102957 | 0.79 | PBRM1 (0.41) | CRBNDDB1IKZF3DRD2PBRM1 | |
| SCHEMBL38662829 | 0.77 | PBRM1 (0.45) | DRD2PBRM1SMARCA2SMARCA4NR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4678638-A1 | NEW E3 UBIQUITIN LIGASE LIGAND, PROTEIN DEGRADATION AGENT AND USE THEREOF | Gluetacs Therapeutics (Shanghai) Co., Ltd. (CN) | 2026-01-14 | — | — | EP | claimed |
| WO-2024188209-A1 | NEW E3 UBIQUITIN LIGASE LIGAND, PROTEIN DEGRADATION AGENT AND USE THEREOF | 标新生物医药科技(上海)有限公司 | 2024-09-19 | — | — | WO | claimed |
| EP-4678638-A1 | NEW E3 UBIQUITIN LIGASE LIGAND, PROTEIN DEGRADATION AGENT AND USE THEREOF | Gluetacs Therapeutics (Shanghai) Co., Ltd. (CN) | 2026-01-14 | — | — | EP | disclosed |
| WO-2024188209-A1 | NEW E3 UBIQUITIN LIGASE LIGAND, PROTEIN DEGRADATION AGENT AND USE THEREOF | 标新生物医药科技(上海)有限公司 | 2024-09-19 | — | — | WO | disclosed |