Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PBRM1 | Q86U86 | 18/20 | 0.45 |
| ▸ | SMARCA2 | P51531 | 15/20 | 0.45 |
| ▸ | SMARCA4 | P51532 | 15/20 | 0.45 |
| ▸ | NR1I2 | O75469 | 8/20 | 0.45 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 4/20 | 0.37 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL38664597 | 0.88 | PBRM1 (0.60) | PBRM1SMARCA2SMARCA4NR1I2BRD4 | |
| SCHEMBL38662678 | 0.85 | PBRM1 (0.42) | PBRM1SMARCA2SMARCA4NR1I2BRD4 | |
| SCHEMBL31331532 | 0.79 | PBRM1 (0.37) | PBRM1SMARCA2SMARCA4NR1I2 | |
| SCHEMBL31101071 | 0.79 | PBRM1 (0.41) | PBRM1SMARCA2SMARCA4NR1I2BRD4 | |
| SCHEMBL31330765 | 0.78 | PBRM1 (0.40) | PBRM1SMARCA2SMARCA4NR1I2BRD4 | |
| SCHEMBL31101161 | 0.78 | SMARCA2 (0.39) | PBRM1SMARCA2SMARCA4NR1I2BRD4 | |
| SCHEMBL31099658 | 0.77 | CRBN (0.42) | PBRM1SMARCA2SMARCA4NR1I2DRD2 | |
| SCHEMBL31102957 | 0.77 | PBRM1 (0.41) | PBRM1SMARCA2SMARCA4NR1I2BRD4 | |
| SCHEMBL23772832 | 0.77 | PBRM1 (0.53) | PBRM1SMARCA2SMARCA4NR1I2BRD4 | |
| SCHEMBL31103189 | 0.76 | PBRM1 (0.39) | PBRM1SMARCA2SMARCA4NR1I2BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122070278-A | Bifunctional protein degradation agent containing aryl substituted heteroaryl and application thereof | 标新生物医药科技(上海)有限公司 | 2026-05-19 | — | — | CN | disclosed |