Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.75 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.75 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.69 |
| ▸ | MEN1 | O00255 | 2/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.69 |
| ▸ | GRIK1 | P39086 | 14/20 | 0.64 |
| ▸ | RAB9A | P51151 | 1/20 | 0.61 |
| ▸ | PKM | P14618 | 1/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6750019 | 1.00 | KDM4E (0.75) | KDM4EHSD17B10ALDH1A1MEN1KMT2A | |
| SCHEMBL7045036 | 0.86 | KDM4E (1.00) | KDM4EHSD17B10ALDH1A1MEN1KMT2A | |
| SCHEMBL29183052 | 0.85 | GRIK1 (0.68) | KDM4EALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL1307133 | 0.84 | MEN1 (0.68) | KDM4EHSD17B10ALDH1A1MEN1KMT2A | |
| SCHEMBL7080579 | 0.83 | MEN1 (0.75) | KDM4EHSD17B10ALDH1A1MEN1KMT2A | |
| SCHEMBL5928755 | 0.83 | ABL1 (0.58) | KDM4EHSD17B10ALDH1A1MEN1KMT2A | |
| SCHEMBL11843933 | 0.82 | MAPT (0.57) | KDM4EHSD17B10ALDH1A1SMN1; SMN2GRIK1 | |
| SCHEMBL7255416 | 0.82 | GRIK1 (0.67) | KDM4EALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7846225 | 0.82 | GRIK1 (0.64) | KDM4EALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL1321725 | 0.81 | KDM4E (0.63) | KDM4EHSD17B10ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4705287-A1 | SMALL MOLECULE HUMANIN MIMETICS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2026-03-11 | — | — | EP | disclosed |
| WO-2024226731-A1 | SMALL MOLECULE HUMANIN MIMETICS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2024-10-31 | — | — | WO | disclosed |
| CN-118420528-A | Preparation method of 7-halogeno-6-nitro-1, 4-dihydro-quinoline-4-ketone-3-carbonitrile | 浙江普洛家园药业有限公司 | 2024-08-02 | — | — | CN | disclosed |