Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 16/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.68 |
| ▸ | MEN1 | O00255 | 2/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.68 |
| ▸ | RAB9A | P51151 | 1/20 | 0.60 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6750019 | 0.85 | KDM4E (0.75) | GRIK1KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL7846225 | 0.85 | GRIK1 (0.64) | GRIK1KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL7255416 | 0.85 | GRIK1 (0.67) | GRIK1KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL1975830 | 0.85 | KDM4E (0.55) | GRIK1KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL31102464 | 0.85 | KDM4E (0.75) | GRIK1KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL1016189 | 0.85 | KDM4E (0.74) | KDM4EALDH1A1 | |
| SCHEMBL11603313 | 0.84 | GRIK1 (0.62) | GRIK1KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL14521237 | 0.82 | GRIK1 (0.60) | GRIK1KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL7761150 | 0.82 | KDM4E (0.74) | GRIK1KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL1308714 | 0.82 | MEN1 (0.76) | GRIK1KDM4EALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115710276-B | 7-fatty amine substituted tryptamine ketone derivative, preparation method and application thereof | 贵州大学 | 2024-04-05 | — | — | CN | disclosed |