Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PBRM1 | Q86U86 | 10/20 | 0.39 |
| ▸ | SMARCA2 | P51531 | 8/20 | 0.39 |
| ▸ | SMARCA4 | P51532 | 8/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.33 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.32 |
| ▸ | TRPC5 | Q9UL62 | 1/20 | 0.31 |
| ▸ | SCD | O00767 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31100309 | 0.90 | PBRM1 (0.50) | PBRM1SMARCA2SMARCA4NR1I2BRD4 | |
| SCHEMBL31101071 | 0.89 | PBRM1 (0.41) | PBRM1SMARCA2SMARCA4NR1I2BRD4 | |
| SCHEMBL31099748 | 0.88 | SMARCA2 (0.38) | PBRM1SMARCA2SMARCA4NR1I2BRD4 | |
| SCHEMBL31102957 | 0.85 | PBRM1 (0.41) | PBRM1SMARCA2SMARCA4NR1I2BRD4 | |
| SCHEMBL31101161 | 0.84 | SMARCA2 (0.39) | PBRM1SMARCA2SMARCA4NR1I2BRD4 | |
| SCHEMBL31101965 | 0.78 | PBRM1 (0.53) | PBRM1SMARCA2SMARCA4NR1I2BRD4 | |
| SCHEMBL31101575 | 0.78 | SMARCA2 (0.38) | PBRM1SMARCA2SMARCA4NR1I2BRD4 | |
| SCHEMBL31101015 | 0.78 | PBRM1 (0.49) | PBRM1SMARCA2SMARCA4NR1I2BRD4 | |
| SCHEMBL31100448 | 0.77 | PBRM1 (0.52) | PBRM1SMARCA2SMARCA4NR1I2BRD4 | |
| SCHEMBL38662829 | 0.76 | PBRM1 (0.45) | PBRM1SMARCA2SMARCA4NR1I2BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4678638-A1 | NEW E3 UBIQUITIN LIGASE LIGAND, PROTEIN DEGRADATION AGENT AND USE THEREOF | Gluetacs Therapeutics (Shanghai) Co., Ltd. (CN) | 2026-01-14 | — | — | EP | claimed |
| WO-2024188209-A1 | NEW E3 UBIQUITIN LIGASE LIGAND, PROTEIN DEGRADATION AGENT AND USE THEREOF | 标新生物医药科技(上海)有限公司 | 2024-09-19 | — | — | WO | claimed |
| EP-4678638-A1 | NEW E3 UBIQUITIN LIGASE LIGAND, PROTEIN DEGRADATION AGENT AND USE THEREOF | Gluetacs Therapeutics (Shanghai) Co., Ltd. (CN) | 2026-01-14 | — | — | EP | disclosed |
| WO-2024188209-A1 | NEW E3 UBIQUITIN LIGASE LIGAND, PROTEIN DEGRADATION AGENT AND USE THEREOF | 标新生物医药科技(上海)有限公司 | 2024-09-19 | — | — | WO | disclosed |