SCHEMBL31103199

SCHEMBL31103199

O=C1CCC(c2cncc(F)c2CBr)C(=O)N1

nearest known ligand 0.47

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CRBN Q96SW2 19/20 0.47
DDB1 Q16531 16/20 0.47
POLB P06746 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31102521 0.87 CRBN (0.43) CRBNDDB1
SCHEMBL31100124 0.87 CRBN (0.43) CRBNDDB1
SCHEMBL31099993 0.82 CRBN (0.47) CRBNDDB1POLB
SCHEMBL32660366 0.81 CRBN (0.39) CRBNDDB1
SCHEMBL31099791 0.80 CRBN (0.39) CRBNDDB1POLB
SCHEMBL31102402 0.76 DDB1 (0.49) CRBNDDB1
SCHEMBL31102789 0.75 CRBN (0.43) CRBNDDB1POLB
SCHEMBL31100751 0.75 CRBN (0.58) CRBNDDB1POLB
SCHEMBL31103225 0.74 CRBN (0.43) CRBNDDB1POLB
SCHEMBL31101357 0.74 CRBN (0.43) CRBNDDB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4678638-A1 NEW E3 UBIQUITIN LIGASE LIGAND, PROTEIN DEGRADATION AGENT AND USE THEREOF Gluetacs Therapeutics (Shanghai) Co., Ltd. (CN) 2026-01-14 EP claimed
WO-2024188209-A1 NEW E3 UBIQUITIN LIGASE LIGAND, PROTEIN DEGRADATION AGENT AND USE THEREOF 标新生物医药科技(上海)有限公司 2024-09-19 WO claimed
EP-4678638-A1 NEW E3 UBIQUITIN LIGASE LIGAND, PROTEIN DEGRADATION AGENT AND USE THEREOF Gluetacs Therapeutics (Shanghai) Co., Ltd. (CN) 2026-01-14 EP disclosed