SCHEMBL32660366

SCHEMBL32660366

O=C1CCC(c2cncc(F)c2CCS(=O)(=O)O)C(=O)N1

nearest known ligand 0.39

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CRBN Q96SW2 20/20 0.39
DDB1 Q16531 12/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL32660650 0.84 CRBN (0.39) CRBNDDB1
SCHEMBL31100124 0.81 CRBN (0.43) CRBNDDB1
SCHEMBL31102521 0.81 CRBN (0.43) CRBNDDB1
SCHEMBL31103199 0.81 CRBN (0.47) CRBNDDB1
SCHEMBL32660350 0.79 CRBN (0.36) CRBNDDB1
SCHEMBL31099791 0.79 CRBN (0.39) CRBNDDB1
SCHEMBL32660445 0.78 CRBN (0.38) CRBNDDB1
SCHEMBL32660643 0.77 CRBN (0.37) CRBNDDB1
SCHEMBL32660693 0.76 CRBN (0.47) CRBNDDB1
SCHEMBL32660422 0.76 CRBN (0.38) CRBNDDB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4678638-A1 NEW E3 UBIQUITIN LIGASE LIGAND, PROTEIN DEGRADATION AGENT AND USE THEREOF Gluetacs Therapeutics (Shanghai) Co., Ltd. (CN) 2026-01-14 EP claimed
EP-4678638-A1 NEW E3 UBIQUITIN LIGASE LIGAND, PROTEIN DEGRADATION AGENT AND USE THEREOF Gluetacs Therapeutics (Shanghai) Co., Ltd. (CN) 2026-01-14 EP disclosed