Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.45 |
| ▸ | HPGD | P15428 | 6/20 | 0.45 |
| ▸ | LMNA | P02545 | 5/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.44 |
| ▸ | TUBB | P07437 | 2/20 | 0.44 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.44 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.44 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.44 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.44 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.44 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.44 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.44 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.44 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.44 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.44 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.44 |
| ▸ | TUBB2B | Q9BVA1 | 2/20 | 0.44 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL311126 | 0.90 | HPGD (0.43) | KDM4EHPGDLMNAHSD17B10ALDH1A1 | |
| SCHEMBL312803 | 0.89 | ALDH1A1 (0.41) | KDM4EHPGDLMNAHSD17B10ALDH1A1 | |
| SCHEMBL312017 | 0.88 | ALDH1A1 (0.41) | KDM4EHPGDLMNAHSD17B10ALDH1A1 | |
| SCHEMBL10215441 | 0.85 | KDM4E (0.45) | KDM4EHPGDLMNAHSD17B10ALDH1A1 | |
| SCHEMBL313232 | 0.84 | HPGD (0.46) | KDM4EHPGDLMNAHSD17B10ALDH1A1 | |
| SCHEMBL10215439 | 0.81 | TP53 (0.42) | KDM4EHPGDLMNAALDH1A1TUBB4A | |
| SCHEMBL312712 | 0.81 | HPGD (0.43) | KDM4EHPGDLMNAHSD17B10ALDH1A1 | |
| SCHEMBL312527 | 0.78 | MEN1 (0.46) | KDM4EHPGDLMNAHSD17B10ALDH1A1 | |
| SCHEMBL312706 | 0.77 | KDM4E (0.61) | KDM4EHPGDLMNAHSD17B10ALDH1A1 | |
| SCHEMBL312241 | 0.76 | ALDH1A1 (0.43) | KDM4EHPGDLMNAHSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8093273-B2 | Flavanoids and isoflavanoids for the prevention and treatment of cardiovascular diseases | RESVERLOGIX CORP. (CA) | 2012-01-10 | — | — | US | disclosed |
| EP-2332527-A2 | Flavanoids and Isoflavanoids for the prevention and treatment of cardiovascular diseases | RESVERLOGIX CORP. (CA) | 2011-06-15 | — | — | EP | disclosed |