Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | INPPL1 | O15357 | 2/20 | 0.38 |
| ▸ | INPP5A | Q14642 | 2/20 | 0.38 |
| ▸ | INPP5B | P32019 | 1/20 | 0.38 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | AKT1 | P31749 | 1/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2568315 | 0.89 | MAPT (0.44) | MAPTLMNAGAAMAPK1HTT | |
| SCHEMBL497602 | 0.88 | KDM4E (0.47) | MAPTKDM4ELMNAINPPL1INPP5A | |
| Fluoride SCHEMBL31047191 | 0.86 | KDM4E (0.46) | MAPTKDM4ELMNAINPPL1INPP5A | |
| SCHEMBL497309 | 0.84 | MAPT (0.67) | MAPTLMNAGAAMAPK1HTT | |
| SCHEMBL27572156 | 0.83 | INPPL1 (0.44) | MAPTKDM4ELMNAGAAMAPK1 | |
| SCHEMBL28949256 | 0.81 | MAPT (0.59) | MAPTLMNAGAAMAPK1HTT | |
| Toluene SCHEMBL28427945 | 0.81 | GPR84 (0.44) | MAPTKDM4ELMNAGPR84SMN1; SMN2 | |
| Biphenyl SCHEMBL28011477 | 0.80 | MAPT (0.57) | MAPTKDM4ELMNAGAAMAPK1 | |
| Catechol SCHEMBL28207158 | 0.80 | MAPT (0.57) | MAPTKDM4ELMNAGAAMAPK1 | |
| SCHEMBL10884019 | 0.79 | SRC (0.52) | MAPTKDM4ELMNAGPR84NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118647372-A | Liquid resin extended release oral naltrexone formulations for the treatment of autism related disorders | 阿达瓦克治疗公司 | 2024-09-13 | — | — | CN | disclosed |
| CN-118591598-A | Non-fluorinated surfactants for floor care coatings | 巴斯夫欧洲公司 | 2024-09-03 | — | — | CN | disclosed |