Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.53 |
| ▸ | PIM1 | P11309 | 7/20 | 0.53 |
| ▸ | CISD1 | Q9NZ45 | 6/20 | 0.53 |
| ▸ | PIM2 | Q9P1W9 | 6/20 | 0.53 |
| ▸ | TTR | P02766 | 1/20 | 0.53 |
| ▸ | MAOB | P27338 | 2/20 | 0.49 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.49 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.49 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.49 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.49 |
| ▸ | MTOR | P42345 | 2/20 | 0.49 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.49 |
| ▸ | CLK1 | P49759 | 2/20 | 0.49 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.49 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.49 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.49 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25282524 | 1.00 | ADAMTS5 (0.53) | ADAMTS5PIM1CISD1PIM2TTR | |
| SCHEMBL25239927 | 1.00 | ADAMTS5 (0.53) | ADAMTS5PIM1CISD1PIM2TTR | |
| SCHEMBL30479904 | 1.00 | ADAMTS5 (0.53) | ADAMTS5PIM1CISD1PIM2TTR | |
| SCHEMBL25287160 | 0.88 | ADAMTS5 (0.56) | ADAMTS5PIM1CISD1PIM2TTR | |
| SCHEMBL25248590 | 0.88 | ADAMTS5 (0.56) | ADAMTS5PIM1CISD1PIM2TTR | |
| SCHEMBL30479903 | 0.85 | PIM1 (0.67) | PIM1CISD1PIM2TTRMAOB | |
| SCHEMBL30479912 | 0.85 | PIM1 (0.67) | PIM1CISD1PIM2TTRMAOB | |
| SCHEMBL25286245 | 0.85 | PIM1 (0.67) | PIM1CISD1PIM2TTRMAOB | |
| SCHEMBL25286244 | 0.85 | PIM1 (0.67) | PIM1CISD1PIM2TTRMAOB | |
| SCHEMBL15091290 | 0.82 | PIM1 (0.75) | ADAMTS5PIM1CISD1PIM2TTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250066347-A1 | SUBSTITUTED THIAZOLIDINEDIONE DERIVATIVE COMPOUND, AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING CANCER, COMPRISING SAME | MEDIFIC, INC. (KR) | 2025-02-27 | — | — | US | claimed |
| EP-4455143-A1 | SUBSTITUTED THIAZOLIDINEDIONE DERIVATIVE COMPOUND, AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING CANCER, COMPRISING SAME | Medific, Inc. (KR) | 2024-10-30 | — | — | EP | claimed |
| CN-118591539-A | Substituted thiazolidinedione derivative compounds and pharmaceutical composition for preventing or treating cancer comprising the same | (株)美迪菲 | 2024-09-03 | — | — | CN | claimed |
| US-20250066347-A1 | SUBSTITUTED THIAZOLIDINEDIONE DERIVATIVE COMPOUND, AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING CANCER, COMPRISING SAME | MEDIFIC, INC. (KR) | 2025-02-27 | — | — | US | disclosed |
| EP-4455143-A1 | SUBSTITUTED THIAZOLIDINEDIONE DERIVATIVE COMPOUND, AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING CANCER, COMPRISING SAME | Medific, Inc. (KR) | 2024-10-30 | — | — | EP | disclosed |
| CN-118591539-A | Substituted thiazolidinedione derivative compounds and pharmaceutical composition for preventing or treating cancer comprising the same | (株)美迪菲 | 2024-09-03 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250066347-A1 | SUBSTITUTED THIAZOLIDINEDIONE DERIVATIVE COMPOUND, AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING CANCER, COMPRISING SAME | SREBF1, SREBF2, SP1 | ADAMTS5 2398/4885PIM1 922/4885CISD1 341/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.