Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAK1 | Q13153 | 5/20 | 0.57 |
| ▸ | KIT | P10721 | 9/20 | 0.53 |
| ▸ | AKT2 | P31751 | 2/20 | 0.50 |
| ▸ | RPS6KB1 | P23443 | 3/20 | 0.49 |
| ▸ | RPS6KA5 | O75582 | 2/20 | 0.49 |
| ▸ | RPS6KA4 | O75676 | 2/20 | 0.49 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.49 |
| ▸ | RPS6KA2 | Q15349 | 2/20 | 0.49 |
| ▸ | RPS6KA1 | Q15418 | 2/20 | 0.49 |
| ▸ | RPS6KB2 | Q9UBS0 | 2/20 | 0.49 |
| ▸ | RPS6KA6 | Q9UK32 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL15732523 | 0.87 | RPS6KB1 (0.52) | PAK1KITAKT2RPS6KB1RPS6KA5 | |
| Hydrochloric Acid SCHEMBL15732684 | 0.87 | LMNA (0.56) | PAK1KITAKT2RPS6KB1RPS6KA5 | |
| Hydrochloric Acid SCHEMBL15732602 | 0.84 | RPS6KB1 (0.60) | PAK1KITAKT2RPS6KB1RPS6KA5 | |
| Hydrochloric Acid SCHEMBL15732520 | 0.83 | RPS6KB1 (0.59) | PAK1KITAKT2RPS6KB1RPS6KA5 | |
| Hydrochloric Acid SCHEMBL15732524 | 0.81 | RPS6KB1 (0.57) | PAK1KITAKT2RPS6KB1RPS6KA5 | |
| Hydrochloric Acid SCHEMBL15732649 | 0.80 | RPS6KB1 (0.64) | PAK1AKT2RPS6KB1RPS6KA5RPS6KA4 | |
| SCHEMBL10161369 | 0.79 | RPS6KB1 (0.54) | PAK1KITAKT2RPS6KB1RPS6KA5 | |
| SCHEMBL311788 | 0.79 | RPS6KB1 (0.73) | PAK1KITAKT2RPS6KB1RPS6KA5 | |
| Hydrochloric Acid SCHEMBL312213 | 0.79 | RPS6KB1 (0.74) | PAK1KITAKT2RPS6KB1RPS6KA5 | |
| SCHEMBL311403 | 0.78 | RPS6KB1 (0.51) | PAK1KITAKT2RPS6KB1RPS6KA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120071490-A1 | P70 S6 KINASE INHIBITORS | ELI LILLY AND COMPANY (US) | 2012-03-22 | — | — | US | disclosed |
| US-8093383-B2 | P70 S6 kinase inhibitors | ELI LILLY AND COMPANY (US) | 2012-01-10 | — | — | US | disclosed |
| US-20090163714-A1 | P70 S6 KINASE INHIBITORS | ELI LILLY AND COMPANY | 2009-06-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090163714-A1 | P70 S6 KINASE INHIBITORS | RPS6KA6, RPS6KA1, RPS6KA2 | PAK1 349/4885KIT 504/4885AKT2 80/4885 |
| US-20120071490-A1 | P70 S6 KINASE INHIBITORS | RPS6KA6, RPS6KA1, RPS6KA2 | PAK1 349/4885KIT 504/4885AKT2 80/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.