Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 15/20 | 0.38 |
| ▸ | BTK | Q06187 | 2/20 | 0.37 |
| ▸ | RXRA | P19793 | 1/20 | 0.37 |
| ▸ | RXRB | P28702 | 1/20 | 0.37 |
| ▸ | RXRG | P48443 | 1/20 | 0.37 |
| ▸ | HCK | P08631 | 4/20 | 0.37 |
| ▸ | SRC | P12931 | 3/20 | 0.37 |
| ▸ | MAPK13 | O15264 | 2/20 | 0.37 |
| ▸ | EGFR | P00533 | 2/20 | 0.37 |
| ▸ | FYN | P06241 | 2/20 | 0.37 |
| ▸ | JAK3 | P52333 | 2/20 | 0.37 |
| ▸ | MAPK12 | P53778 | 2/20 | 0.37 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.37 |
| ▸ | ABL1 | P00519 | 2/20 | 0.36 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.36 |
| ▸ | YES1 | P07947 | 1/20 | 0.36 |
| ▸ | LYN | P07948 | 1/20 | 0.36 |
| ▸ | FGR | P09769 | 1/20 | 0.36 |
| ▸ | KIT | P10721 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31106116 | 0.89 | LCK (0.38) | LCKBTKHCKSRCMAPK13 | |
| SCHEMBL31105889 | 0.88 | HCK (0.44) | LCKBTKRXRARXRBRXRG | |
| SCHEMBL31106079 | 0.85 | LCK (0.38) | LCKBTKRXRARXRBRXRG | |
| SCHEMBL31106019 | 0.84 | LCK (0.45) | LCKBTKHCKSRCMAPK13 | |
| SCHEMBL31105942 | 0.83 | LCK (0.42) | LCKBTKHCKSRCMAPK13 | |
| SCHEMBL31105895 | 0.83 | LCK (0.44) | LCKBTKRXRARXRBRXRG | |
| SCHEMBL31105865 | 0.82 | LCK (0.46) | LCKBTKHCKSRCMAPK13 | |
| SCHEMBL31105912 | 0.82 | MAPK14 (0.50) | LCKBTKRXRARXRBRXRG | |
| SCHEMBL31705188 | 0.81 | LCK (0.52) | LCKHCKSRCMAPK13EGFR | |
| SCHEMBL31105893 | 0.80 | LCK (0.41) | LCKRXRARXRBRXRGHCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024184520-A1 | BIARYLAMIDE DERIVATIVES AND THEIR USE IN THE TREATMENT OF PROLIFERATIVE DISORDERS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2024-09-12 | — | — | WO | disclosed |