Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 3/20 | 0.47 |
| ▸ | LYN | P07948 | 1/20 | 0.47 |
| ▸ | TXK | P42681 | 1/20 | 0.47 |
| ▸ | SYK | P43405 | 1/20 | 0.47 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.47 |
| ▸ | LCK | P06239 | 11/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | SRC | P12931 | 3/20 | 0.41 |
| ▸ | ABL1 | P00519 | 2/20 | 0.41 |
| ▸ | HCK | P08631 | 3/20 | 0.41 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | FYN | P06241 | 1/20 | 0.41 |
| ▸ | JAK3 | P52333 | 1/20 | 0.41 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.41 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.41 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.41 |
| ▸ | ITK | Q08881 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31105890 | 0.79 | BTK (0.47) | BTKLYNTXKSYKMAPK14 | |
| SCHEMBL31105905 | 0.79 | MAPK14 (0.41) | BTKMAPK14LCKSRCABL1 | |
| SCHEMBL31706857 | 0.77 | LCK (0.63) | MAPK14LCKSRCABL1HCK | |
| SCHEMBL31106086 | 0.76 | LCK (0.47) | MAPK14LCKSRCHCKMAPK13 | |
| SCHEMBL31106087 | 0.75 | LCK (0.45) | LYNMAPK14LCKSRCABL1 | |
| SCHEMBL31105892 | 0.74 | LCK (0.48) | BTKLYNMAPK14LCKSRC | |
| SCHEMBL31106126 | 0.73 | MAPK14 (0.61) | MAPK14LCKSRCHCKMAPK13 | |
| SCHEMBL31106169 | 0.73 | LCK (0.48) | LYNMAPK14LCKSRCABL1 | |
| SCHEMBL20530776 | 0.72 | MAPK14 (0.64) | BTKLYNMAPK14LCKSRC | |
| SCHEMBL20530773 | 0.72 | MAPK14 (0.64) | BTKLYNMAPK14LCKSRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024184520-A1 | BIARYLAMIDE DERIVATIVES AND THEIR USE IN THE TREATMENT OF PROLIFERATIVE DISORDERS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2024-09-12 | — | — | WO | disclosed |