Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | MAP4K1 | Q92918 | 3/20 | 0.35 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | ALPL | P05186 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24558302 | 1.00 | TSHR (0.36) | TSHRMAP4K1NR4A2HTTALPL | |
| SCHEMBL29474183 | 0.76 | MAP4K1 (0.39) | MAP4K1ALOX15 | |
| SCHEMBL28811081 | 0.76 | MAP4K1 (0.39) | MAP4K1ALOX15 | |
| SCHEMBL31638752 | 0.76 | TSHR (0.38) | TSHRMAP4K1HTTALPLALDH1A1 | |
| SCHEMBL3577890 | 0.73 | MAP4K1 (0.38) | TSHRMAP4K1HTTALPLALDH1A1 | |
| SCHEMBL30929191 | 0.73 | TSHR (0.44) | TSHRNR4A2HTTALPLMEN1 | |
| SCHEMBL25103996 | 0.73 | TSHR (0.44) | TSHRNR4A2HTTALPLMEN1 | |
| SCHEMBL24558296 | 0.73 | KDM4E (0.37) | TSHRHTTMEN1ALDH1A1KMT2A | |
| SCHEMBL31107241 | 0.73 | KDM4E (0.37) | TSHRHTTMEN1ALDH1A1KMT2A | |
| SCHEMBL29474177 | 0.71 | IDO1 (0.34) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113508118-B | Fused tricyclic compounds useful as anticancer agents | 阿斯利康(瑞典)有限公司 | 2024-07-19 | — | — | CN | disclosed |