Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TARBP2 | Q15633 | 1/20 | 0.41 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.39 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | GLP1R | P43220 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31107210 | 0.79 | ALDH1A1 (0.40) | TARBP2TRPM8NPC1LMNARAB9A | |
| SCHEMBL29693174 | 0.79 | ALDH1A1 (0.40) | TARBP2TRPM8NPC1LMNARAB9A | |
| SCHEMBL24558259 | 0.78 | TARBP2 (0.39) | TARBP2CYP1A2TSHRGLP1RKDM4E | |
| SCHEMBL2929292 | 0.75 | KDM4E (0.55) | RAB9ACA12CA1CA2CA7 | |
| SCHEMBL3706487 | 0.74 | GLP1R (0.48) | TRPM8NPC1LMNARAB9ACA12 | |
| SCHEMBL17362538 | 0.74 | TARBP2 (0.42) | TARBP2NPC1RAB9ATSHRCYP2C19 | |
| SCHEMBL31345635 | 0.74 | GLP1R (0.48) | TRPM8NPC1LMNARAB9ACA12 | |
| SCHEMBL1819905 | 0.72 | TSHR (0.48) | LMNACA12CA1CA2CA7 | |
| SCHEMBL30200423 | 0.72 | TARBP2 (0.46) | TARBP2NPC1LMNARAB9ACYP1A2 | |
| SCHEMBL15968597 | 0.72 | CA12 (0.46) | NPC1LMNARAB9ACA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113508118-B | Fused tricyclic compounds useful as anticancer agents | 阿斯利康(瑞典)有限公司 | 2024-07-19 | — | — | CN | disclosed |