Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 2/20 | 0.46 |
| ▸ | NOS3 | P29474 | 1/20 | 0.46 |
| ▸ | NOS2 | P35228 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.33 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.31 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6565617 | 1.00 | NOS1 (0.46) | NOS1NOS3NOS2CA12CA14 | |
| SCHEMBL28062530 | 0.87 | NOS1 (0.46) | NOS1NOS3NOS2CA12CA14 | |
| SCHEMBL919727 | 0.86 | NOS1 (0.46) | NOS1NOS3NOS2CA12CA14 | |
| SCHEMBL311871 | 0.86 | NOS1 (0.46) | NOS1NOS3NOS2CA12CA14 | |
| SCHEMBL320155 | 0.86 | NOS1 (0.46) | NOS1NOS3NOS2CA12CA14 | |
| Hydrochloric Acid SCHEMBL8848963 | 0.85 | NOS1 (0.45) | NOS1NOS3NOS2CA12CA14 | |
| Hydrochloric Acid SCHEMBL919725 | 0.84 | NOS1 (0.45) | NOS1NOS3NOS2CA12CA14 | |
| Hydrochloric Acid SCHEMBL146832 | 0.84 | NOS1 (0.45) | NOS1NOS3NOS2CA12CA14 | |
| SCHEMBL19858386 | 0.84 | NOS1 (0.45) | NOS1NOS3NOS2CA12CA14 | |
| SCHEMBL304099 | 0.84 | NOS1 (0.45) | NOS1NOS3NOS2CA12CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025235389-A1 | P53 MODULATORS | NESTED THERAPEUTICS, INC. (US) | 2025-11-13 | — | — | WO | disclosed |
| WO-2024215802-A1 | BENZOFURANYL AND BENZOTHIENYL COMPOUNDS AS P53 MODULATORS | NESTED THERAPEUTICS, INC. (US) | 2024-10-17 | — | — | WO | disclosed |