Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.36 |
| ▸ | CDC14B | O60729 | 1/20 | 0.30 |
| ▸ | CDC14A | Q9UNH5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31107771 | 0.79 | LOXL2 (0.35) | LOXL2CDC14BCDC14A | |
| SCHEMBL31107772 | 0.79 | LOXL2 (0.39) | LOXL2 | |
| SCHEMBL31495824 | 0.76 | LOXL2 (0.34) | LOXL2CDC14BCDC14A | |
| SCHEMBL31107760 | 0.73 | LOXL2 (0.33) | LOXL2 | |
| SCHEMBL19596146 | 0.70 | — | — | |
| SCHEMBL31107723 | 0.69 | LOXL2 (0.39) | LOXL2 | |
| SCHEMBL31107739 | 0.69 | — | — | |
| SCHEMBL31534803 | 0.68 | LOXL2 (0.32) | LOXL2 | |
| SCHEMBL30358399 | 0.67 | ELANE (0.34) | LOXL2 | |
| SCHEMBL29208181 | 0.67 | LOXL2 (0.34) | LOXL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025055856-A1 | P53-Y220C-SELECTIVE SMALL-MOLECULE REACTIVATOR COMPOUND, PHARMACEUTICAL COMPOSITION, AND USE THEREOF | 长春金赛药业有限责任公司 | 2025-03-20 | — | — | WO | disclosed |
| WO-2024215802-A1 | BENZOFURANYL AND BENZOTHIENYL COMPOUNDS AS P53 MODULATORS | NESTED THERAPEUTICS, INC. (US) | 2024-10-17 | — | — | WO | disclosed |